Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection.

• Hoofdauteurs: Xiangguo Qiu (Auteur), Lisa Fernando (Auteur), P Leno Melito (Auteur), Jonathan Audet (Auteur), Heinz Feldmann (Auteur), Gary Kobinger (Auteur), Judie B Alimonti (Auteur), Steven M Jones (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Ebola virus (EBOV) causes acute hemorrhagic fever in humans and non-human primates with mortality rates up to 90%. So far there are no effective treatments available. This study evaluates the protective efficacy of 8 monoclonal antibodies (MAbs) against Ebola glycoprotein in mice and guinea pigs. Im...