Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation

• Príomhchruthaitheoirí: Norikazu Kiguchi (Údar), Haruka Sakaguchi (Údar), Yui Kadowaki (Údar), Fumihiro Saika (Údar), Yohji Fukazawa (Údar), Shinsuke Matsuzaki (Údar), Shiroh Kishioka (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2017-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Inflammatory macrophages play a fundamental role in neuropathic pain. In this study, we demonstrate the effects of peripheral interleukin-13 (IL-13) on neuropathic pain after partial sciatic nerve (SCN) ligation (PSL) in mice. IL-13 receptor α1 was upregulated in accumulating macrophages in the inju...