Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation

• Váldodahkkit: Norikazu Kiguchi (Dahkki), Haruka Sakaguchi (Dahkki), Yui Kadowaki (Dahkki), Fumihiro Saika (Dahkki), Yohji Fukazawa (Dahkki), Shinsuke Matsuzaki (Dahkki), Shiroh Kishioka (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2017-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Inflammatory macrophages play a fundamental role in neuropathic pain. In this study, we demonstrate the effects of peripheral interleukin-13 (IL-13) on neuropathic pain after partial sciatic nerve (SCN) ligation (PSL) in mice. IL-13 receptor α1 was upregulated in accumulating macrophages in the inju...