OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

• المؤلفون الرئيسيون: Ravinder Kaur (مؤلف), Christopher Aiken (مؤلف), Ludivine Coudière Morrison (مؤلف), Radhika Rao (مؤلف), Marc R. Del Bigio (مؤلف), Shravanti Rampalli (مؤلف), Tamra Werbowetski-Ogilvie (مؤلف)
• التنسيق: كتاب
• منشور في: The Company of Biologists, 2015-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has mad...