Hypothalamic POMC neuron-specific knockout of MC4R affects insulin sensitivity by regulating Kir2.1

• Asıl Yazarlar: Hengru Guo (Yazar), Ying Xin (Yazar), Saifei Wang (Yazar), Xiaoning Zhang (Yazar), Yanqi Ren (Yazar), Bo Qiao (Yazar), Hongjiang Li (Yazar), Jing Wu (Yazar), Xiao Hao (Yazar), Lijun Xu (Yazar), Yushan Yan (Yazar), Haohao Zhang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2024-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Imbalance in energy regulation is a major cause of insulin resistance and diabetes. Melanocortin-4 receptor (MC4R) signaling at specific sites in the central nervous system has synergistic but non-overlapping functions. However, the mechanism by which MC4R in the arcuate nucleus...