Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators

• Үндсэн зохиолчид: Roberto Sabbadini (Зохиогч), Emanuela Pesce (Зохиогч), Alice Parodi (Зохиогч), Eleonora Mustorgi (Зохиогч), Santina Bruzzone (Зохиогч), Nicoletta Pedemonte (Зохиогч), Monica Casale (Зохиогч), Enrico Millo (Зохиогч), Elena Cichero (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Cystic fibrosis (CF) is caused by different mutations related to the cystic fibrosis transmembrane regulator protein (CFTR), with F508del being the most common. Pioneering the development of CFTR modulators, thanks to the development of effective correctors or potentiators, more recent studies deepl...