Screening of E. coli β-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization

• Huvudskapare: Preeti Pandey (Författare, medförfattare), Vijay Verma (Författare, medförfattare), Suman Kumar Dhar (Författare, medförfattare), Samudrala Gourinath (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: MDPI AG, 2018-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

The characteristic of interaction with various enzymes and processivity-promoting nature during DNA replication makes β-clamp an important drug target. Helicobacter pylori (H. pylori) have several unique features in DNA replication machinery that makes it different from other microorganisms. To find...