Screening of E. coli β-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization

• Κύριοι συγγραφείς: Preeti Pandey (Συγγραφέας), Vijay Verma (Συγγραφέας), Suman Kumar Dhar (Συγγραφέας), Samudrala Gourinath (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2018-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The characteristic of interaction with various enzymes and processivity-promoting nature during DNA replication makes β-clamp an important drug target. Helicobacter pylori (H. pylori) have several unique features in DNA replication machinery that makes it different from other microorganisms. To find...