A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug-Drug Interaction Perpetrators

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug-Drug Interaction Perpetrators

The antifungal ketoconazole, which is mainly used for dermal infections and treatment of Cushing's syndrome, is prone to drug-food interactions (DFIs) and is well known for its strong drug-drug interaction (DDI) potential. Some of ketoconazole's potent inhibitory activity can be attributed...

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Main Authors: Fatima Zahra Marok (Author), Jan-Georg Wojtyniak (Author), Laura Maria Fuhr (Author), Dominik Selzer (Author), Matthias Schwab (Author), Johanna Weiss (Author), Walter Emil Haefeli (Author), Thorsten Lehr (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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