Investigation of MDMA Inhibitory Effect on CytochromeP450 3A4 in Isolated Perfused Rat Liver Model Using Tramadol

• Главные авторы: Behjat Sheikholeslami (Автор), Zahra Tootoonchi (Автор), Hoda Lavasani (Автор), Yalda Hosseinzadeh Ardakani (Автор), Mohammadreza Rouini (Автор)
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• Опубликовано: Tabriz University of Medical Sciences, 2021-06-01T00:00:00Z.
• Предметы: article
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Purpose: MDMA (methylenedioxymethamphetamine) is a synthetic compound, which is a structurally derivative of amphetamine. Also, it acts like an amphetamine, structurally, and functionally. MDMA uses mechanism-based inhibition, to inhibit isoenzyme CYP2D6. It can also inhibit other isoenzymes contrib...