Investigation of MDMA Inhibitory Effect on CytochromeP450 3A4 in Isolated Perfused Rat Liver Model Using Tramadol

• Glavni autori: Behjat Sheikholeslami (Autor), Zahra Tootoonchi (Autor), Hoda Lavasani (Autor), Yalda Hosseinzadeh Ardakani (Autor), Mohammadreza Rouini (Autor)
• Format: Knjiga
• Izdano: Tabriz University of Medical Sciences, 2021-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Purpose: MDMA (methylenedioxymethamphetamine) is a synthetic compound, which is a structurally derivative of amphetamine. Also, it acts like an amphetamine, structurally, and functionally. MDMA uses mechanism-based inhibition, to inhibit isoenzyme CYP2D6. It can also inhibit other isoenzymes contrib...