Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration

• मुख्य लेखकों: Washim Khan (लेखक), Yan-Hong Wang (लेखक), Narayan D. Chaurasiya (लेखक), N. P. Dhammika Nanayakkara (लेखक), H. M. Bandara Herath (लेखक), Kerri A. Harrison (लेखक), Gray Dale (लेखक), Donald A. Stanford (लेखक), Eric P. Dahl (लेखक), James D. McChesney (लेखक), Waseem Gul (लेखक), Mahmoud A. ElSohly (लेखक), David Jollow (लेखक), Babu L. Tekwani (लेखक), Larry A. Walker (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Primaquine (PQ) is an 8-aminoquinoline antimalarial, active against dormant Plasmodium vivax hypnozoites and P. falciparum mature gametocytes. PQ is currently used for P. vivax radical cure and prevention of malaria transmission. PQ is a racemic drug and since the metabolism and pharmacology of PQ&#...