Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

• Главные авторы: Kent Pedersen (Автор), Helle Andersen (Автор), Christian Fledelius (Автор), Jens Juul Holst (Автор), Sara Toftegaard Hjuler (Автор), Rune Ehrenreich Kuhre (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2023-03-01T00:00:00Z.
• Предметы: article
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Objective: A fundamental difference between physiological and pharmacological studies in rats and humans is that withdrawal of blood from conscious rats necessitates restraint which inevitably inflicts a higher level of stress. We investigated the impact of handling on acute glucose regulation and s...