Penetration Depth of Propylene Glycol, Sodium Fluorescein and Nile Red into the Skin Using Non-Invasive Two-Photon Excited FLIM

• Egile Nagusiak: Mohammad Alhibah (Egilea), Marius Kröger (Egilea), Sabine Schanzer (Egilea), Loris Busch (Egilea), Jürgen Lademann (Egilea), Ingeborg Beckers (Egilea), Martina C. Meinke (Egilea), Maxim E. Darvin (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The stratum corneum (<i>SC</i>) forms a strong barrier against topical drug delivery. Therefore, understanding the penetration depth and pathways into the <i>SC</i> is important for the efficiency of drug delivery and cosmetic safety. In this study, TPT-FLIM (two-photon tomog...