Iron scavenging and suppression of collagen cross-linking underlie antifibrotic effects of carnosine in the heart with obesity

• Egile Nagusiak: Islam A. Berdaweel (Egilea), T. Blake Monroe (Egilea), Amany A. Alowaisi (Egilea), Jolonda C. Mahoney (Egilea), I-Chau Liang (Egilea), Kaitlyn A. Berns (Egilea), Dylan Gao (Egilea), Jared M. McLendon (Egilea), Ethan J. Anderson (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Oral consumption of histidyl dipeptides such as l-carnosine has been suggested to promote cardiometabolic health, although therapeutic mechanisms remain incompletely understood. We recently reported that oral consumption of a carnosine analog suppressed markers of fibrosis in liver of obese mice, bu...