Development of Atomoxetine-Loaded NLC In Situ Gel for Nose-to-Brain Delivery: Optimization, In Vitro, and Preclinical Evaluation
The present study investigates the brain-targeted efficiency of atomoxetine (AXT)-loaded nanostructured lipid carrier (NLC)-laden thermosensitive in situ gel after intranasal administration. AXT-NLC was prepared by the melt emulsification ultrasonication method and optimized using the Box-Behnken de...
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Main Authors: | Dibyalochan Mohanty (Author), Omar Awad Alsaidan (Author), Ameeduzzafar Zafar (Author), Trishala Dodle (Author), Jeetendra Kumar Gupta (Author), Mohd Yasir (Author), Anshuman Mohanty (Author), Mohammad Khalid (Author) |
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Format: | Book |
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MDPI AG,
2023-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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