l-Glutamate Enhances Methylmercury Toxicity by Synergistically Increasing Oxidative Stress

• Hoofdauteurs: Sirirat Amonpatumrat (Auteur), Hiroyuki Sakurai (Auteur), Pattama Wiriyasermkul (Auteur), Narakorn Khunweeraphong (Auteur), Shushi Nagamori (Auteur), Hidekazu Tanaka (Auteur), Pawinee Piyachaturawat (Auteur), Yoshikatsu Kanai (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2008-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Methylmercury (MeHg) is a well-known environmental toxicant. With its lipophilic nature and high reactivity to sulfhydryl groups, it is widely distributed and accumulated in the body to damage cells. Oxidative stress is proposed as a major mechanism underlying the cytotoxic action of MeHg. In the pr...