Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine

• 主要な著者: Sean R. Moore (著者), Jill Pruszka (著者), Jefferson Vallance (著者), Eitaro Aihara (著者), Toru Matsuura (著者), Marshall H. Montrose (著者), Noah F. Shroyer (著者), Christian I. Hong (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2014-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Disruption of circadian rhythms is a risk factor for several human gastrointestinal (GI) diseases, ranging from diarrhea to ulcers to cancer. Four-dimensional tissue culture models that faithfully mimic the circadian clock of the GI epithelium would provide an invaluable tool to understand circadian...