CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer

• Main Authors: Leilei Yang (Author), Chengfeng Fang (Author), Jiaju Han (Author), Yufeng Ren (Author), Zaiping Yang (Author), Lingyan Shen (Author), Dinghai Luo (Author), Ruili Zhang (Author), Yan Chen (Author), Shenkang Zhou (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ferroptosis, a form of cell death characterized by lipid peroxidation, plays a crucial role in tumor suppression, offering novel avenues for cancer therapy. Previous studies have indicated that high levels of cyclin-dependent kinase subunit 2 (CKS2) promote the progression of var...