CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer

• Päätekijät: Leilei Yang (Tekijä), Chengfeng Fang (Tekijä), Jiaju Han (Tekijä), Yufeng Ren (Tekijä), Zaiping Yang (Tekijä), Lingyan Shen (Tekijä), Dinghai Luo (Tekijä), Ruili Zhang (Tekijä), Yan Chen (Tekijä), Shenkang Zhou (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2024-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Ferroptosis, a form of cell death characterized by lipid peroxidation, plays a crucial role in tumor suppression, offering novel avenues for cancer therapy. Previous studies have indicated that high levels of cyclin-dependent kinase subunit 2 (CKS2) promote the progression of var...