Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam

• Prif Awduron: A. Scott Emmert (Awdur), Eri Iwasawa (Awdur), Crystal Shula (Awdur), Preston Schultz (Awdur), Diana Lindquist (Awdur), R. Scott Dunn (Awdur), Elizabeth M. Fugate (Awdur), Yueh-Chiang Hu (Awdur), Francesco T. Mangano (Awdur), June Goto (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: The Company of Biologists, 2019-11-01T00:00:00Z.
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Neonatal hydrocephalus affects about one child per 1000 births and is a major congenital brain abnormality. We previously discovered a gene mutation within the coiled-coil domain-containing 39 (Ccdc39) gene, which causes the progressive hydrocephalus (prh) phenotype in mice due to lack of ependymal-...