Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

• Main Authors: Yeonho Son (Author), Yoon Keun Cho (Author), Abhirup Saha (Author), Hyun-Jung Kwon (Author), Ji-Hyun Park (Author), Minsu Kim (Author), Young-Suk Jung (Author), Sang-Nam Kim (Author), Cheoljun Choi (Author), Je-Kyung Seong (Author), Rayanne B. Burl (Author), James G. Granneman (Author), Yun-Hee Lee (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...