Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

• Автори: Yeonho Son (Автор), Yoon Keun Cho (Автор), Abhirup Saha (Автор), Hyun-Jung Kwon (Автор), Ji-Hyun Park (Автор), Minsu Kim (Автор), Young-Suk Jung (Автор), Sang-Nam Kim (Автор), Cheoljun Choi (Автор), Je-Kyung Seong (Автор), Rayanne B. Burl (Автор), James G. Granneman (Автор), Yun-Hee Lee (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2020-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Objective: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...