Synthesis and Modification of Morphine and Codeine, Leading to Diverse Libraries with Improved Pain Relief Properties

• Hauptverfasser: Mona Kamelan Zargar Zarin (Verfasst von), Wim Dehaen (Verfasst von), Peyman Salehi (Verfasst von), Amir Ata Bahmani Asl (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Morphine and codeine, two of the most common opioids, are widely used in the clinic for different types of pain. Morphine is one of the most potent agonists for the <i>μ</i>-opioid receptor, leading to the strongest analgesic effect. However, due to their association with serious side ef...