Synthesis and Modification of Morphine and Codeine, Leading to Diverse Libraries with Improved Pain Relief Properties

• Egile Nagusiak: Mona Kamelan Zargar Zarin (Egilea), Wim Dehaen (Egilea), Peyman Salehi (Egilea), Amir Ata Bahmani Asl (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Morphine and codeine, two of the most common opioids, are widely used in the clinic for different types of pain. Morphine is one of the most potent agonists for the <i>μ</i>-opioid receptor, leading to the strongest analgesic effect. However, due to their association with serious side ef...