Convection Enhanced Delivery in the Setting of High-Grade Gliomas

• Auteurs principaux: Chibueze D. Nwagwu (Auteur), Amanda V. Immidisetti (Auteur), Michael Y. Jiang (Auteur), Oluwasegun Adeagbo (Auteur), David C. Adamson (Auteur), Anne-Marie Carbonell (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood-brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity due to systemic exposure. Convection-enhanced delivery...