Convection Enhanced Delivery in the Setting of High-Grade Gliomas

• Main Authors: Chibueze D. Nwagwu (Author), Amanda V. Immidisetti (Author), Michael Y. Jiang (Author), Oluwasegun Adeagbo (Author), David C. Adamson (Author), Anne-Marie Carbonell (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood-brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity due to systemic exposure. Convection-enhanced delivery...