Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab

• প্রধান লেখক: S. Signa (লেখক), E. Campione (লেখক), M. Rusmini (লেখক), S. Chiesa (লেখক), A. Grossi (লেখক), A. Omenetti (লেখক), R. Caorsi (লেখক), G. M. Viglizzo (লেখক), M. Galluzzo (লেখক), L. Bianchi (লেখক), M. Talamonti (লেখক), A. Orlandi (লেখক), A. Martini (লেখক), I. Ceccherini (লেখক), M. Gattorno (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2019-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Autosomal dominant gain of function mutations in caspase recruitment domain family member 14 (CARD14) is a rare condition associated with plaque-type psoriasis, generalized pustular psoriasis, palmoplantar pustular psoriasis and pityriasis rubra pilaris. Recently, a new CARD14 -a...