Prevalence of inversions in introns 1 and 22 of the factor VIII gene and inhibitors in patients from southern Brazil

Prevalence of inversions in introns 1 and 22 of the factor VIII gene and inhibitors in patients from southern Brazil

ABSTRACT Objectives: The development of antibodies (inhibitors) against exogenous factors is the main complication in the treatment of hemophilia. Both genetic and non-genetic factors are related to inhibitor development. Among the genetic factors, the type of mutation that caused the disease is one...

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Main Authors: Maria Cristina S. M. Corrêa (Author), Euripides Ferreira (Author), Marcelo T. A. Veiga (Author), Eliane Bandinelli (Author), Clévia Rosset (Author)
Format: Book
Published: Sociedade Brasileira de Patologia Clínica.
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