Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones

• Asıl Yazarlar: Perihan A. Elzahhar (Yazar), Rana A. Alaaeddine (Yazar), Rasha Nassra (Yazar), Azza Ismail (Yazar), Hala F. Labib (Yazar), Mohamed G. Temraz (Yazar), Ahmed S. F. Belal (Yazar), Ahmed F. El-Yazbi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The work reported herein describes the synthesis of a new series of anti-inflammatory pyrazolyl thiazolones. In addition to COX-2/15-LOX inhibition, these hybrids exerted their anti-inflammatory actions through novel mechanisms. The most active compounds possessed COX-2 inhibitory activities compara...