Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.

• Autores principales: Thomas R Lane (Autor), Christopher Massey (Autor), Jason E Comer (Autor), Manu Anantpadma (Autor), Joel S Freundlich (Autor), Robert A Davey (Autor), Peter B Madrid (Autor), Sean Ekins (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Recent outbreaks of the Ebola virus (EBOV) have focused attention on the dire need for antivirals to treat these patients. We identified pyronaridine tetraphosphate as a potential candidate as it is an approved drug in the European Union which is currently used in combination with artesunate as a tr...