Rapid and sensitive point-of-care detection of Leptospira by RPA-CRISPR/Cas12a targeting lipL32.

• Hoofdauteurs: Sirawit Jirawannaporn (Auteur), Umaporn Limothai (Auteur), Sasipha Tachaboon (Auteur), Janejira Dinhuzen (Auteur), Patcharakorn Kiatamornrak (Auteur), Watchadaporn Chaisuriyong (Auteur), Jom Bhumitrakul (Auteur), Oraphan Mayuramart (Auteur), Sunchai Payungporn (Auteur), Nattachai Srisawat (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2022-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<h4>Background</h4>One of the key barriers preventing rapid diagnosis of leptospirosis is the lack of available sensitive point-of-care testing. This study aimed to develop and validate a clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 12a (CRI...