Synthesis of Pyrrolo[3,4-<i>b</i>]pyridin-5-ones via Ugi-Zhu Reaction and In Vitro-In Silico Studies against Breast Carcinoma

• Үндсэн зохиолчид: Ivette Morales-Salazar (Зохиогч), Carlos E. Garduño-Albino (Зохиогч), Flora P. Montes-Enríquez (Зохиогч), Dania A. Nava-Tapia (Зохиогч), Napoleón Navarro-Tito (Зохиогч), Leonardo David Herrera-Zúñiga (Зохиогч), Eduardo González-Zamora (Зохиогч), Alejandro Islas-Jácome (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-11-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

An Ugi-Zhu three-component reaction (UZ-3CR) coupled in a one-pot manner to a cascade process (<i>N</i>-acylation/<i>aza</i> Diels-Alder cycloaddition/decarboxylation/dehydration) was performed to synthesize a series of pyrrolo[3,4-<i>b</i>]pyridin-5-ones in 20% t...