Phosphatase-independent functions of SHP2 and its regulation by small molecule compounds
SHP2 is a non-receptor protein tyrosine phosphatase encoded by the PTPN11 gene in human. Clinically, SHP2 has been identified as a causal factor of several diseases, such as Noonan syndrome, LEOPARD syndrome as well as myeloid malignancies. Interestingly, both loss-of-function and gain-of-function m...
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| フォーマット: | 図書 |
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Elsevier,
2020-11-01T00:00:00Z.
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| 請求記号: |
A1234.567 |
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| 所蔵 1 | 利用可 |