Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors

• मुख्य लेखकों: Takuya Maemoto (लेखक), Miho Tada (लेखक), Takuma Mihara (लेखक), Noriko Ueyama (लेखक), Hideaki Matsuoka (लेखक), Katsuya Harada (लेखक), Takayuki Yamaji (लेखक), Kiyoharu Shirakawa (लेखक), Satoru Kuroda (लेखक), Atsushi Akahane (लेखक), Akinori Iwashita (लेखक), Nobuya Matsuoka (लेखक), Seitaro Mutoh (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2004-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Adenosine A1 receptors in the brain are believed to play an important role in brain functioning. We have discovered a novel adenosine A1 receptor antagonist, FR194921 (2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3(2H)-pyridazinone), and characterized the pharmacological activi...