Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors

• Автори: Takuya Maemoto (Автор), Miho Tada (Автор), Takuma Mihara (Автор), Noriko Ueyama (Автор), Hideaki Matsuoka (Автор), Katsuya Harada (Автор), Takayuki Yamaji (Автор), Kiyoharu Shirakawa (Автор), Satoru Kuroda (Автор), Atsushi Akahane (Автор), Akinori Iwashita (Автор), Nobuya Matsuoka (Автор), Seitaro Mutoh (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2004-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Adenosine A1 receptors in the brain are believed to play an important role in brain functioning. We have discovered a novel adenosine A1 receptor antagonist, FR194921 (2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3(2H)-pyridazinone), and characterized the pharmacological activi...