Sample Size Requirements of a Pharmaceutical Material Library: A Case in Predicting Direct Compression Tablet Tensile Strength by Latent Variable Modeling

• Hauptverfasser: Junjie Cao (VerfasserIn), Haoran Shen (VerfasserIn), Shuying Zhao (VerfasserIn), Xiao Ma (VerfasserIn), Liping Chen (VerfasserIn), Shengyun Dai (VerfasserIn), Bing Xu (VerfasserIn), Yanjiang Qiao (VerfasserIn)
• Format: Buch
• Veröffentlicht: MDPI AG, 2024-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The material library is an emerging, new data-driven approach for developing pharmaceutical process models. How many materials or samples should be involved in a particular application scenario is unclear, and the impact of sample size on process modeling is worth discussing. In this work, the direc...