Maternal antibiotic exposure increases total islet number and volume in the neonatal pancreas and reduces HbA1c and insulitis in adult female non‐obese diabetic mice

• Auteurs principaux: Camilla Hartmann Friis Hansen (Auteur), Martin Haupt‐Jorgensen (Auteur), Karsten Buschard (Auteur), Bente Pakkenberg (Auteur), Lukasz Krych (Auteur), Axel Kornerup Hansen (Auteur)
• Format: Livre
• Publié: Wiley, 2023-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Early antibiotic treatment changes susceptibility to disease in rodent models for type 1 diabetes, but the impact that gestational antibiotics may have on pancreatic embryogenesis and β cell function later in life is still unknown. Methods Our aim was to determine whether gestati...