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Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients

Abstract Background Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD). Methods A single dose of 100 mg quinine was given...

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Main Authors:	Hadi Molanaei (Author), Abdul Rashid Qureshi (Author), Olof Heimbürger (Author), Bengt Lindholm (Author), Ulf Diczfalusy (Author), Björn Anderstam (Author), Leif Bertilsson (Author), Peter Stenvinkel (Author)
Format:	Book
Published:	BMC, 2018-06-01T00:00:00Z.
Subjects:	article
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