Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells

• المؤلفون الرئيسيون: Mohamed eSaeed (مؤلف), Stefan eJacob (مؤلف), Louis eSandjo (مؤلف), Yoshikazu eSugimoto (مؤلف), Hassan eKhalid (مؤلف), Till eOpatz (مؤلف), Eckhard eThines (مؤلف), Thomas eEfferth (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Multidrug resistance (MDR) is a prevailing phenomenon leading to chemotherapy treatment failure in cancer patients. In the current study two known cytotoxic pseudoguaianolide sesquiterpene lactones; neombrosin (1) and damsin (2) that circumvent MDR were identified. The two cytotoxic compounds were i...