Methylene Blue Is a Nonspecific Protein-Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

• Hoofdauteurs: Sung-Ting Chuang (Auteur), Henrietta Papp (Auteur), Anett Kuczmog (Auteur), Rebecca Eells (Auteur), Jose M. Condor Capcha (Auteur), Lina A. Shehadeh (Auteur), Ferenc Jakab (Auteur), Peter Buchwald (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We have previously identified methylene blue, a tricyclic phenothiazine dye approved for clinical use for the treatment of methemoglobinemia and for other medical applications as a small-molecule inhibitor of the protein-protein interaction (PPI) between the spike protein of the SARS-CoV-2 coronavir...