Methylene Blue Is a Nonspecific Protein-Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

• Váldodahkkit: Sung-Ting Chuang (Dahkki), Henrietta Papp (Dahkki), Anett Kuczmog (Dahkki), Rebecca Eells (Dahkki), Jose M. Condor Capcha (Dahkki), Lina A. Shehadeh (Dahkki), Ferenc Jakab (Dahkki), Peter Buchwald (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We have previously identified methylene blue, a tricyclic phenothiazine dye approved for clinical use for the treatment of methemoglobinemia and for other medical applications as a small-molecule inhibitor of the protein-protein interaction (PPI) between the spike protein of the SARS-CoV-2 coronavir...