U1A is a positive regulator of the expression of heterologous and cellular genes involved in cell proliferation and migration

• Автори: Eric Rovira (Автор), Beatriz Moreno (Автор), Nerea Razquin (Автор), Roland Hjerpe (Автор), Monika Gonzalez-Lopez (Автор), Rosa Barrio (Автор), Igor Ruiz de los Mozos (Автор), Jernej Ule (Автор), Fernando Pastor (Автор), Lorea Blazquez (Автор), Puri Fortes (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2022-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Here, we show that direct recruitment of U1A to target transcripts can increase gene expression. This is a new regulatory role, in addition to previous knowledge showing that U1A decreases the levels of U1A mRNA and other specific targets. In fact, genome-wide, U1A more often increases rather than r...