The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages

• Главные авторы: Orna Ernst (Автор), Yifat Glucksam-Galnoy (Автор), Muhammad Athamna (Автор), Iris Ben-Dror (Автор), Hadar Ben-Arosh (Автор), Galit Levy-Rimler (Автор), Iain D. C. Fraser (Автор), Tsaffrir Zor (Автор)
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• Опубликовано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предметы: article
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Interleukin-10 (IL-10) is a key anti-inflammatory cytokine, secreted by macrophages and other immune cells to attenuate inflammation. Autocrine type I interferons (IFNs) largely mediate the delayed expression of IL-10 by LPS-stimulated macrophages. We have previously shown that IL-10 is synergistica...