SP600125 Attenuates Nicotine-Related Aortic Aneurysm Formation by Inhibiting Matrix Metalloproteinase Production and CC Chemokine-Mediated Macrophage Migration

• Asıl Yazarlar: Zhen-Zhen Guo (Yazar), Qun-An Cao (Yazar), Zong-Zhuang Li (Yazar), Li-Ping Liu (Yazar), Zhi Zhang (Yazar), Ya-Juan Zhu (Yazar), Guang Chu (Yazar), Qiu-Yan Dai (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2016-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Nicotine, a major chemical component of cigarettes, plays a pivotal role in the development of abdominal aortic aneurysm (AAA). c-Jun N-terminal kinase (JNK) has been demonstrated to participate in elastase-induced AAA. This study aimed to elucidate whether the JNK inhibitor SP600125 can attenuate n...