Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

• প্রধান লেখক: Muenyi Clarisse S (লেখক), States Vanessa A (লেখক), Masters Joshua H (লেখক), Fan Teresa W (লেখক), Helm C William (লেখক), States J Christopher (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2011-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death in the USA. Recurrence rates are high after front-line therapy and most patients eventually die from platinum (Pt) - resistant disease. Cisplatin resist...