Enhancement of zaleplon oral bioavailability using optimized self-nano emulsifying drug delivery systems and its effect on sleep quality among a sample of psychiatric patients

• Główni autorzy: Maha K. A. Khalifa (Autor), Hoda A. Salem (Autor), Seham M. Shawky (Autor), Heba A. Eassa (Autor), Asmaa M. Elaidy (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The aim of this work is to develop self-nano emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of zaleplon (Zal) as a poorly water-soluble drug. Moreover, the bioavailability and the effect on the quality of sleep among a sample of psychiatric patients is to be assessed....