Enhancement of zaleplon oral bioavailability using optimized self-nano emulsifying drug delivery systems and its effect on sleep quality among a sample of psychiatric patients

• Main Authors: Maha K. A. Khalifa (Author), Hoda A. Salem (Author), Seham M. Shawky (Author), Heba A. Eassa (Author), Asmaa M. Elaidy (Author)
• 格式: 图书
• 出版: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The aim of this work is to develop self-nano emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of zaleplon (Zal) as a poorly water-soluble drug. Moreover, the bioavailability and the effect on the quality of sleep among a sample of psychiatric patients is to be assessed....