Molecular Dynamics Study of Human MTHFR Wild-Type and A222V Mutant-Type: A Computational Approach

• Päätekijät: Michael Resta Surya Yanuar (Tekijä), Dita Maria Virginia (Tekijä), Enade Perdana Istyastono (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Universitas Sanata Dharma, 2023-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Methylenetetrahydrofolate reductase (MTHFR) is an essential enzyme for the homeostasis and metabolism of intracellular folate. However, it is known that one of the commonly found MTHFR gene SNPs (A222V) causes a decrease in activity which decreases folate levels and increases the accumulation of hom...