Design, synthesis, and biological evaluation of piperazine derivatives involved in the 5-HT1AR/BDNF/PKA pathway
AbstractIn this study, four series of piperazine derivatives were designed, synthesised and subjected to biological test, and compound 6a with potential antidepressant activity was obtained. An affinity assay of compound 6a with 5-hydroxytryptamine (serotonin, 5-HT)1A receptor (5-HT1AR) was undertak...
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Main Authors: | , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2024-12-01T00:00:00Z.
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Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |